36 similar games
Games like Mainframe
Browser games that play like Mainframe, closest match first. Lime means it runs right here.

Mainframe is roguelite tower defense Currently the game features - 3 Campaign Sectors, featuring 24 total levels - 12 Unique Towers, each with there own 3 pathway ultimates & visuals - 5 Detailed Bosses - 12 Unqiue… The games below have the most in common with it — real time strategy (rts), strategy, tower defense — ranked by how closely they match, favouring the ones you can play right here in your browser.
Top picks
The 10 closest to Mainframe
- Yorg.ioPlays here
Yorg.io is a game about supply chains and zombies. In common: tower defense, real time strategy (rts), strategy.
- HegemarchPlays here
Hegemarch is a real-time space strategy roguelite played in the web browser. In common: roguelite, real time strategy (rts), strategy.
- Creeper WorldPlays here
Imagine an enemy that is everywhere and moves like a giant, organic mass across the map. In common: tower defense, real time strategy (rts), strategy.
- Gotchi GuardiansPlays here
Adapt, strategize, and dominate your rivals in this multiplayer roguelite tower defense brawler. In common: tower defense, real time strategy (rts), strategy.
- AlderunPlays here
Alderun is a free-to-play fantasy strategy RPG that blends real-time strategy with MOBA-style hero combat. In common: tower defense, real time strategy (rts), strategy.
- Battle of CastlesPlays on battleofcastles.com
Play online for free and without ads with Battle Of Castles. In common: tower defense, real time strategy (rts), strategy.
- SminerPlays on lightning8113.itch.io
Mine resources and summon minions to protect your tower! In common: tower defense, real time strategy (rts), strategy.
- Second StrikePlays here
SECOND STRIKE is a free world war simulator in the browser. In common: real time strategy (rts), sandbox, strategy.
- Sneaky ForestPlays on sinedsem.itch.io
A Tower Defense game made at Siberian Game Jam. In common: tower defense, real time strategy (rts), strategy.
- Sneaky MonstersPlays on honeycombsgames.itch.io
Tower Defense with unusual mechanics, where the AI sends the most inconvenient monsters and you have to constantly sell and rebuild towers. In common: tower defense, real time strategy (rts), strategy.
All matches
Every game like Mainframe
PlayableYorg.io
Zombies · 2018
PlayableHegemarch
Procedural Generation · 2026
PlayableCreeper World
Post Apocalyptic · 2007
PlayableGotchi Guardians
Tower Defense · 2025
PlayableAlderun
Tower Defense · 2026
PlayableBattle of Castles
Tower Defense · 2020
PlayableSminer
Tower Defense · 2024
PlayableEarly accessSecond Strike
War · 2026
PlayableSneaky Forest
Tower Defense · 2021
PlayableAlphaSneaky Monsters
Tower Defense · 2023
PlayableAlphaExtinction Level Event
Survival
PlayableAlphaBlockMill
Blockchain · 2023
PlayableClash of Vikings
Real Time Tactics
PlayablePardus
Aliens · 2004
PlayableNikola's Fate
Tower Defense · 2020
PlayableColony Defenders TD
Tower Defense · 2011
PlayableYouTD 2
Tower Defense · 2023

Colony Battle
Ants · 2021

GemCraft
Tower Defense · 2008

Desktop Tower Defense
Tower Defense · 2007

Grub Guardian
Tower Defense · 2012

Zombie Misfits
Tower Defense
PlayableEarly accessMoon Watch
Bullet Hell · 2024
PlayableBetaOath of the Necromancer
Exploration · 2024
PlayableXterium: War of Alliances
Space · 2017
PlayableMAD: Mutually Assured Destruction
Action · 2007
PlayableGameBuddies.io
Tower Defense
PlayableMushroom Madness 2
Tower Defense · 2010
PlayableAlphaTwo-Timin' Towers
Tower Defense · 2020
PlayableWASD Wizard
Tower Defense · 2025
PlayableEarly accessVerticopolis
Life Simulation · 2026
PlayableGame Over Gopher
Tower Defense · 2014

Majukes Tower Defense
Tower Defense · 2023
PlayableAlphaHolder of Place
Roguelike · 2024
PlayablePokeVoid
Roguelike · 2025
PlayableSnowlord
Tower Defense · 2023